The coronary risk of cyclo-oxygenase-2 inhibitors in patients with a previous myocardial infarction
نویسندگان
چکیده
منابع مشابه
Evaluation of cytotoxicity mechanism of two cyclo-oxygenase-2 inhibitors in leukemia cell line
Introduction: Leukemia is considered one of the main causes of death, and current chemotherapeutic agents are unable to provide optimal responses due to chemo-resistance. Therefore, there is a constant need for new drugs. Cyclooxygenase- 2 (COX-2) inhibitors can be helpful by reducing the necessary dose of routine chemotherapeutic drugs. Herein, we evaluated the cytotoxicity activity as well...
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BACKGROUND Cyclo-oxygenase-2 (COX-2) is induced in cardiomyocytes only in response to stress, such as ischaemia. OBJECTIVE To assess COX-2 expression at the site of recent myocardial infarction. METHODS COX-2 expression was evaluated by specific immunostaining in cardiomyocytes from 23 subjects who died 10-60 days after acute myocardial infarction. The relation between COX-2 myocardial expr...
متن کاملElectrophysiological testing in high-risk patients with previous myocardial infarction.
Letters to the Editor will be published, if suitable, as space permits. They should not exceed 1,000 words (typed double-spaced) in length and may be subject to editing or abridgment. Dr. Wellens raises several important issues in his recent editorial comment1 regarding the role of electrophysiological testing in risk stratification and treatment of patients with previous myocar-dial infarction...
متن کاملRisk of myocardial infarction in patients taking cyclo-oxygenase-2 inhibitors or conventional non-steroidal anti-inflammatory drugs: population based nested case-control analysis.
AIMS To determine the comparative risk of myocardial infarction in patients taking cyclo-oxygenase-2 and other non-steroidal anti-inflammatory drugs (NSAIDs) in primary care between 2000 and 2004; to determine these risks in patients with and without pre-existing coronary heart disease and in those taking and not taking aspirin. DESIGN Nested case-control study. SETTING 367 general practice...
متن کاملEvaluation of ejection fraction in patients with acute myocardial infarction undergoing percutaneous coronary intervention
Introduction: Percutaneous coronary intervention (PCI) is a reperfusion strategy to increase life expectancy and ejection fraction (EF) in ST-segment elevation myocardial infarction (STEMI) patients. We investigated the effect of location, severity, type of lesion, number and type of vessel involved and time of angioplasty on the increase in EF in STEMI patients undergoing primary PCI (P-PCI) a...
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ژورنال
عنوان ژورنال: Heart
سال: 2005
ISSN: 1355-6037
DOI: 10.1136/hrt.2006.089367